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Theodoris CV*, Xiao L, Chopra A, Chaffin MD, Al Sayed ZR, Hill MC, Mantineo H, Brydon EM, Zeng Z, Liu XS, Ellinor PT*. Transfer learning enables predictions in network biology. Nature. 2023 May 31; Epub ahead of print. (*co-corresponding authors)

Lynch AW*, Theodoris CV*, Long HW, Brown M, Liu XS, Meyer CA. MIRA: joint regulatory modeling of multimodal expression and chromatin accessibility in single cellsNat Methods. 2022 09; 19(9):1097-1108. (*co-first authors)

Theodoris CV, Zhou P, Liu L, Zhang Y, Nishino T, Huang Y, Kostina A, Ranade SS, Gifford CA, Uspenskiy V, Malashicheva A, Ding S, Srivastava D. Network-based screen in iPSC-derived cells reveals therapeutic candidate for heart valve disease. Science. 2021 02 12; 371(6530).

Theodoris CV, Mourkioti F, Huang Y, Ranade SS, Liu L, Blau HM, Srivastava D. Long telomeres protect against age-dependent cardiac disease caused by NOTCH1 haploinsufficiency. J Clin Invest. 2017 May 01; 127(5):1683-1688.

Barruet E, Morales BM, Lwin W, White MP, Theodoris CV, Kim H, Urrutia A, Wong SA, Srivastava D, Hsiao EC. The ACVR1 R206H mutation found in fibrodysplasia ossificans progressiva increases human induced pluripotent stem cell-derived endothelial cell formation and collagen production through BMP-mediated SMAD1/5/8 signaling.  Stem Cell Res Ther. 2016 08 17; 7(1):115.

White MP, Theodoris CV, Liu L, Collins WJ, Blue KW, Lee JH, Meng X, Robbins RC, Ivey KN, Srivastava D. NOTCH1 regulates matrix gla protein and calcification gene networks in human valve endothelium.  J Mol Cell Cardiol. 2015 Jul; 84:13-23.

Theodoris CV, Li M, White MP, Liu L, He D, Pollard KS, Bruneau BG, Srivastava D. Human disease modeling reveals integrated transcriptional and epigenetic mechanisms of NOTCH1 haploinsufficiency. Cell. 2015 Mar 12; 160(6):1072-86.

Smith J, Kraemer E, Liu H, Theodoris CV, Davidson EH. A spatially dynamic cohort of regulatory genes in the endomesodermal gene network of the sea urchin embryo. Dev Biol. 2008 Jan 15; 313(2):863-75.

Smith J, Theodoris CV, Davidson EH. A gene regulatory network subcircuit drives a dynamic pattern of gene expression. Science. 2007 Nov 02; 318(5851):794-7.

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